Article
Deletion in poly(ADP-ribose)polymerase pseudogene and lung cancer risk.
Carcinogenesis - 1 Jan 1998
Wu X, Hsu T C, Cao S, Lee J J, Amos C I, Spitz M R
Abstract excerpt
The poly(ADP-ribose)polymerase (PADPRP) gene has been implicated in carcinogenesis through its role in DNA repair, replication and recombination. A two-allele polymorphism in the chromosome 13 PADPRP pseudogene has been studied in several racial groups. It has been suggested that the B allele, wh...
Topics
- Black People
- Case-Control Studies
- Cells, Cultured
- Chromosome Mapping
- Chromosomes, Human, Pair 13
- Female
- Gene Deletion
- Genotype
- Humans
- Lung Neoplasms
- Lymphocytes
- Male
- Mexican Americans
