Article
Deletion in poly(ADP-ribose)polymerase pseudogene and lung cancer risk.
Carcinogenesis - 1 Jan 1998
Wu X, Hsu T C, Cao S, Lee J J, Amos C I, Spitz M R
Abstract excerpt
The poly(ADP-ribose)polymerase (PADPRP) gene has been implicated in carcinogenesis through its role in DNA repair, replication and recombination. A two-allele polymorphism in the chromosome 13 PADPRP pseudogene has been studied in several racial groups. It has been suggested that the B allele, which results from a 193-bp deletion in the gene, predisposes to myeloma in Blacks. We assessed the association between...
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