A deletion linked to a poly(ADP-ribose) polymerase gene on chromosome 13q33-qter occurs frequently in the normal black population as well as in multiple tumor DNA.

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Article

A deletion linked to a poly(ADP-ribose) polymerase gene on chromosome 13q33-qter occurs frequently in the normal black population as well as in multiple tumor DNA.

Cancer research - 1 Sept 1990

Bhatia K G, Cherney B W, Huppi K, Magrath I T, Cossman J, Sausville E, Barriga F, Johnson B, Gause B, Bonney G

Abstract excerpt

The nuclear enzyme poly(ADP-ribose) polymerase (PADPRP) is thought to play a role in DNA recombination, replication, and repair. In view of the implication of these processes in tumorigenesis, and based on preliminary evidence which indicated the presence of an extraneous polymorphic restriction fragment for murine PADPRP loci in strains of mice susceptible to plasmacytomas, we investigated correlations between...

Topics

Alleles
Asian People
Black People
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 13
DNA
DNA, Neoplasm
Female
Gene Frequency
Genes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Neoplasms

Poly(ADP-ribose) Polymerases

Reference Values

Restriction Mapping

United States

White People

Source

Open in PubMed

Identifiers

PMID: 2117481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2117481-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A deletion linked to a poly(ADP-ribose) polymerase gene on chromosome 13q33-qter occurs frequently in the normal black population as well as in multiple tumor DNA.PMID 2117481Read ↗

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