Article
Poly(ADP-ribose) polymerase in human breast cancer: a case-control analysis.
Pharmacogenetics - 1 Aug 1997
Hu J J, Roush G C, Dubin N, Berwick M, Roses D F, Harris M N
Abstract excerpt
The importance of a genetic polymorphism (A/B allele) of poly(ADP-ribose) polymerase (PARP) pseudogene on chromosome 13q34-qter, and PARP enzyme activities in the development of human breast cancer were evaluated in a cancer case-control study. A total of 309 Caucasian women (> or = 50 years old)...
Topics
- Aged
- Breast Neoplasms
- Case-Control Studies
- Chromosomes, Human, Pair 13
- DNA, Neoplasm
- Enzyme Induction
- Female
- Genotype
- Humans
- Middle Aged
- Poly(ADP-ribose) Polymerases
- Pseudogenes