Article
Mutagen sensitivity as a biological marker of lung cancer risk in African Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 1995
Spitz M R, Hsu T C, Wu X, Fueger J J, Amos C I, Roth J A
Abstract excerpt
Cigarette smoking is the major determinant of lung cancer. However, only a fraction of smokers develops lung cancer; genetically determined susceptibility factors seem to play an important role also. Previous case-control studies have shown that in vitro bleomycin-induced mutagen sensitivity is a...
Topics
- Adenocarcinoma
- Black or African American
- Age Factors
- Biomarkers
- Black People
- Bleomycin
- Carcinoma, Squamous Cell
- Case-Control Studies
- DNA Damage
- Female
- Genetic Predisposition to Disease