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Article

A quantitative assay for assessing allelic proportions by iterative gap ligation.

Nucleic acids research - 15 Feb 1998

Stewart J, Kozlowski P, Sowden M, Messing E, Smith H C

Abstract excerpt

A variety of techniques are currently available for detecting point mutations in DNA. These techniques are frequently not sensitive enough to be applied as quantitative assays in evaluation of relative occurrence of alleles in cases of polymorphism or when variations in allelic gene expression are being evaluated at the level of RNA. We report here the establishment of an iterative gap ligation (IGL) assay that...

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Share to Alleles
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Point Mutation

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 9461454
DOI: 10.1093/nar/26.4.961
PMCID: PMC147360

Genes

IGL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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