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Article

Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint.

Science (New York, N.Y.) - 13 Feb 1998

Kim S H, Lin D P, Matsumoto S, Kitazono A, Matsumoto T

Abstract excerpt

Mad2 is a component of the spindle checkpoint, which delays the onset of anaphase until all chromosomes are attached to the spindle. Mad2 formed a complex with Slp1, a WD (tryptophan-aspartic acid)-repeat protein essential for the onset of anaphase. When the physical interaction between the two proteins was disrupted, the spindle checkpoint was no longer functional. Post-anaphase events such as chromosome...

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Identifiers

PMID: 9461438
DOI: 10.1126/science.279.5353.1045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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