Budding yeast Cdc20: a target of the spindle checkpoint.

doi:10.1126/science.279.5353.1041

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Article

Budding yeast Cdc20: a target of the spindle checkpoint.

Science (New York, N.Y.) - 13 Feb 1998

Hwang L H, Lau L F, Smith D L, Mistrot C A, Hardwick K G, Hwang E S, Amon A, Murray A W

Abstract excerpt

The spindle checkpoint regulates the cell division cycle by keeping cells with defective spindles from leaving mitosis. In the two-hybrid system, three proteins that are components of the checkpoint, Mad1, Mad2, and Mad3, were shown to interact with Cdc20, a protein required for exit from mitosis...

Topics

Amino Acid Sequence
Anaphase
Anaphase-Promoting Complex-Cyclosome
Antigens, CD
Cadherins
Calcium-Binding Proteins
Carrier Proteins
Cdc20 Proteins
Cdh1 Proteins
Cell Cycle Proteins
DNA Damage
DNA Replication
Fungal Proteins
Ligases
Mad2 Proteins
Mitosis
Molecular Sequence Data
Mutation

Source

Open in PubMed

Identifiers

PMID: 9461437
DOI: 10.1126/science.279.5353.1041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9461437-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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