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Article

Toxic thyroid adenoma: absence of DNA mutations of the TSH receptor and Gs alpha.

European journal of endocrinology - 1 Jan 1998

Pinducciu C, Borgonovo G, Arezzo A, Torre G C, Giordano G, Cordera R

Abstract excerpt

DNA point mutations of the TSH receptor and of the alpha subunit of the stimulatory GTP-binding protein (Gs alpha) have been suggested as major causes of hyperfunctioning thyroid adenomas. However, significant differences in the prevalence of these mutations (from 0.3 to 84%) have been found in different populations. The present study was designed to evaluate further the presence of mutations in discrete...

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Source

Identifiers

PMID: 9461313
DOI: 10.1530/eje.0.1380037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Toxic thyroid adenoma: absence of DNA mutations of the TSH receptor and Gs alpha.PMID 9461313Read ↗

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Identification of constitutively activating somatic thyrotropin receptor mutations in a subset of toxic multinodular goiters.Semantic proximity Read ↗

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