Article
[Mutation analysis of p16 gene in non-small cell lung carcinomas].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 1999
Fu S, Wang B, Huang C, Liu Q, Zhang G, Li P
Abstract excerpt
OBJECTIVE: To investigate the role of p16 gene in the tumorigenesis of non-small cell lung carcinomas (NSCLC). METHODS: Homozygous deletion and mutation of exon 2 of p16 genes in 40 NSCLC tissues were analyzed using PCR and dsDNA direct sequencing technique. RESULTS: In 2 NSCLC tissues, homozygou...
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