Article
CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children. French Pediatric HIV Infection Study Group.
JAMA - 28 Jan 1998
Misrahi M, Teglas J P, N'Go N, Burgard M, Mayaux M J, Rouzioux C, Delfraissy J F, Blanche S
Abstract excerpt
CONTEXT: Studies suggest that adults with the CCR5delta32 deletion are less likely to become infected with the human immunodeficiency virus (HIV) and to develop HIV-related disease progression, but the effect of the mutation in children is not known. OBJECTIVE: To study the effect of the CCR5 chemokine receptor mutant allele on mother-to-child transmission of HIV type 1 (HIV-1) and subsequent disease progression...
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