Article
CCR5 haplotypes and mother-to-child HIV transmission in Malawi.
PloS one - 5 Sept 2007
Pedersen Bonnie R, Kamwendo Deborah, Blood Melinda, Mwapasa Victor, Molyneux Malcolm, North Kari, Rogerson Stephen J, Zimmerman Peter, Meshnick Steven R
Abstract excerpt
BACKGROUND: CCR5 and CCR2 gene polymorphisms (SNPs) have been associated with protection against HIV transmission in adults and with delayed progression to AIDS. The CCR5 Delta32 deletion and SNP -2459G are associated with reduced expression of the CCR5 protein. METHODOLOGY/PRINCIPAL FINDINGS: We...
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