Article
Distribution of CCR5delta32 in human immunodeficiency virus-infected children and its relationship to disease course.
Clinical and diagnostic laboratory immunology - 1 Jan 1998
Bakshi S S, Zhang L, Ho D, Than S, Pahwa S G
Abstract excerpt
Homozygosity for a 32-bp deletion in the CCR5 gene (CCR5delta32) has been shown to confer resistance to infection with the macrophage-tropic strain of human immunodeficiency virus (HIV) type 1. We examined the distribution of CCR5delta32 in 47 children (age range, 1.5 to 19 years), of whom 43 were infected with HIV, by the perinatal route (n = 41) or by the intravenous route (n = 2). The infected patients were...
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