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Article

CCR5 genotype and HIV-1 infection in perinatally-exposed infants.

The Journal of infection - 1 Jan 1999

Mas A, Español T, Heredia A, Pedraza M A, Hernandez M, Caragol I, Fernando M, Bertran J M, Alcami J, Soriano V

Abstract excerpt

The CCR5 chemokine receptor is required by non-syncytium HIV-1 strains to infect target cells. A 32 base pair deletion (delta32) in the CCR5 gene causes a structural CCR5 modification that does not permit HIV-1 entry into cells. The rate of the CCR5 delta32 was investigated in 137 children born from HIV-infected mothers. Overall, five (10.6%) of 47 HIV-infected infants showed the defect in heterozygosis vs. eight...

Read the complete abstract on PubMed

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Share to HIV-1
Share to HIV Infections
Share to Infectious Disease Transmission, Vertical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Sequence Deletion

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Source

Identifiers

PMID: 10090498
DOI: 10.1016/s0163-4453(99)90020-8

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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