Article
CCR2B-64I chemokine receptor allele and mother-to-child HIV-1 transmission or disease progression in children. French pediatric HIV infection study group.
Journal of acquired immune deficiency syndromes (1999) - 1 Nov 1999
Teglas J P, N'Go N, Burgard M, Mayaux M J, Rouzioux C, Blanche S, Delfraissy J F, Misrahi M
Abstract excerpt
The beneficial role of a variant of the chemokine receptor CCR2B (CCR2B-641) in the evolution of HIV-1 infection in adults is still controversial. Furthermore, no studies have been performed in HIV-1-infected children. A multicenter and prospective study of 745 infants born to HIV-1-seropositive mothers was performed. The CCR2B-641 allele was studied in 525 non-African children among whom 523 had been previously...
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