Article
Enzyme-linked immunosorbent assay for p53 in gastrointestinal malignancy: comparison with immunohistochemistry.
Histopathology - 1 Nov 1993
Joypaul B V, Vojtesek B, Newman E L, Hopwood D, Grant A, Lane D P, Cuschieri A
Abstract excerpt
Mutations in the p53 nuclear oncogene occur frequently in a wide spectrum of human malignancies and the mutant protein may prove to be a useful diagnostic or prognostic marker. It can be detected in fixed tissues by immunohistochemistry, but the type of fixative and conditions of fixation used ca...
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