p53 genetic alterations, protein expression and autoantibodies in human colorectal carcinoma: A comparative study.

doi:10.3892/ijo.12.4.785

Back to search

Article

p53 genetic alterations, protein expression and autoantibodies in human colorectal carcinoma: A comparative study.

International journal of oncology - 1 Apr 1998

Hallak R, Mueller J, Lotter O, Gansauge S, Gansauge F, el-Deen Jumma M, Montenarh M, Safi F, Beger H

Abstract excerpt

This study investigated a total number of 120 colorectal malignant tumor tissues by applying a new quantitative luminometric assay (LIA)-mat, immunohistochemistry (IHC) (n=100), PCR/SSCP (n=42), and sequencing (n=7). Sera were collected from 235 patients suffering from colorectal carcinoma in add...

Topics

Autoantibodies
Colorectal Neoplasms
Exons
Genes, p53
Humans
Immunohistochemistry
Mutation
Polymerase Chain Reaction
Prognosis
Tumor Suppressor Protein p53

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.