Article
p53 genetic alterations, protein expression and autoantibodies in human colorectal carcinoma: A comparative study.
International journal of oncology - 1 Apr 1998
Hallak R, Mueller J, Lotter O, Gansauge S, Gansauge F, el-Deen Jumma M, Montenarh M, Safi F, Beger H
Abstract excerpt
This study investigated a total number of 120 colorectal malignant tumor tissues by applying a new quantitative luminometric assay (LIA)-mat, immunohistochemistry (IHC) (n=100), PCR/SSCP (n=42), and sequencing (n=7). Sera were collected from 235 patients suffering from colorectal carcinoma in addition to 195 healthy individuals as a control group. Manual ELISA kit was developed to detect p53 autoantibodies in the...
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