Article
In situ quantification of aberrant p53 in colorectal neoplasia.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2000
Smith Steven Jay, Neugut Alfred, Heitjan Daniel, Forde Kenneth, Holt Peter, Santella Regina M, Jiin-Chyuan Luo, Carney Walter, Ward Llewelyn, Brandt-Rauf Paul W
Abstract excerpt
Aberrant p53 protein accumulation was measured immunohistologically in 342 colorectal paraffin-embedded tissue sections from 115 patients (24 with adenocarcinoma, 59 with adenoma and 32 'hospital controls'). Subjective scoring was compared with quantitative cell imaging, including dichotomous (p5...
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