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Article

Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif.

The Journal of biological chemistry - 30 Jan 1998

Flynn P, Mellor H, Palmer R, Panayotou G, Parker P J

Abstract excerpt

PRK1 (PKN) is a serine/threonine kinase that has been shown to be activated by RhoA (Amano, M., Mukai, H., Ono, Y., Chihara, K., Matsui, T., Hamajima, Y., Okawa, K., Iwamatsu, A., and Kaibuchi, K. (1996) Science 271, 648-650). Detailed analysis of the PRK1 region involved in RhoA binding has revealed that two homologous sequences within the HR1 domain (HR1a and HR1b) both bind to RhoA; the third repeat within...

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PMID: 9446575
DOI: 10.1074/jbc.273.5.2698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif.PMID 9446575Read ↗

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