Article
PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation.
The Biochemical journal - 1 Mar 2005
Zhao Zhou-shen, Manser Ed
Abstract excerpt
The Rho GTPases are a family of molecular switches that are critical regulators of signal transduction pathways in eukaryotic cells. They are known principally for their role in regulating the cytoskeleton, and do so by recruiting a variety of downstream effector proteins. Kinases form an importa...
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