Article
Enhancement of Hepatitis B Virus Infection by Noninfectious Subviral Particles
1 Feb 1998
Abstract excerpt
The biological function of the huge excess of subviral particles over virions in hepatitis B virus infections is unknown. Using the duck hepatitis B virus as a model, we unexpectedly found that subviral particles strongly enhance intracellular viral replication and gene expression. This effect is dependent on the multiplicity of infection, the ratio of virions over subviral particles, and the time point of...
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