Article
A test statistic to detect errors in sib-pair relationships.
American journal of human genetics - 1 Jan 1998
Ehm M, Wagner M
Abstract excerpt
Several authors have proposed algorithms to detect Mendelian errors in human genetic linkage data. Most currently available methods use likelihood-based methods on multiplex family data to identify typing or pedigree errors. These algorithms cannot be applied in many sib-pair collections, because...
Topics
- Algorithms
- Female
- Genetic Diseases, Inborn
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Models, Statistical
- Nuclear Family
- Probability