Improved inference of relationship for pairs of individuals.

doi:10.1016/S0002-9297(07)62952-8

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Article

Improved inference of relationship for pairs of individuals.

American journal of human genetics - 1 Nov 2000

Epstein M P, Duren W L, Boehnke M

Abstract excerpt

Linkage analyses of genetic diseases and quantitative traits generally are performed using family data. These studies assume the relationships between individuals within families are known correctly. Misclassification of relationships can lead to reduced or inappropriately increased evidence for...

Topics

Alleles
Chromosome Mapping
Computer Simulation
Diabetes Mellitus, Type 2
Female
Gene Frequency
Genetic Linkage
Genetic Markers
Genetic Testing
Genotype
Humans
Likelihood Functions
Male
Matched-Pair Analysis
Models, Genetic
Multicenter Studies as Topic
Nuclear Family
Pedigree

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