One-tube method for complete HPA-1 genotyping by PCR using sequence-specific primers.

doi:10.1046/j.1365-2141.1997.5013303.x

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Article

One-tube method for complete HPA-1 genotyping by PCR using sequence-specific primers.

British journal of haematology - 1 Dec 1997

Boldt B, Skogen B, Agostini T, Roscetti D, McFarland J

Abstract excerpt

Human platelet antigens (HPA) can be targets for antibody responses that cause life-threatening thrombocytopenia following platelet transfusions or pregnancy. As an aid to diagnosis and prevention, serologic and DNA-based methods have been developed to type HPA. Of the DNA-based strategies, those...

Topics

Alleles
Antigens, Human Platelet
Base Sequence
DNA Primers
Electrophoresis, Agar Gel
Genotype
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Thrombocytopenia

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