Article
High-throughput multiplex single-nucleotide polymorphism analysis for red cell and platelet antigen genotypes.
Transfusion - 1 May 2005
Denomme G A, Van Oene M
Abstract excerpt
BACKGROUND: Transfusion recipients who become alloimmunized to red cell or platelet (PLT) antigens require antigen-negative blood to limit adverse transfusion reactions. Blood collection facilities use regulated and unregulated antibodies to phenotype blood, the cost of which can be prohibitive depending on the antisera and demand. An alternative strategy is to screen blood for these antigens with genomic DNA and...
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