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Article

K-ras and p53 gene mutations in colorectal cancer in 57 Japanese patients.

Fukushima journal of medical science - 1 Jun 1997

Onda M, Abe R, Tsuchiya A, Fukushima T, Ando Y, Yoshida T

Abstract excerpt

Fifty-eight tissue specimens from 57 Japanese patients with colorectal cancer were analyzed for the K-ras and p53 gene mutations by polymerase chain reaction-single strand conformation polymorphism analysis and direct sequencing. K-ras mutations were detected in 21 cases (36.2%) and p53 mutations in 20 cases (34.5%). Eight specimens had both gene mutations. The K-ras mutation was associated with higher degrees of...

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PMID: 9431782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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