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Article

Alterations in K-ras, APC and p53-multiple genetic pathway in colorectal cancer among Indians.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2013

Malhotra Pooja, Anwar Mumtaz, Nanda Neha, Kochhar Rakesh, Wig Jai Dev, Vaiphei Kim, Mahmood Safrun

Abstract excerpt

The incidence of colorectal cancer (CRC) is increasing rapidly in Asian countries during the past few decades, but no comprehensive analysis has been done to find out the exact cause of this disease. In this study, we investigated the frequencies of mutations and expression pattern of K-ras, APC (adenomatosis polyposis coli) and p53 in tumor, adjoining and distant normal mucosa and to correlate these alterations...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23526092
DOI: 10.1007/s13277-013-0734-y

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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