Article
p53 Gene mutations in sporadic colorectal carcinoma in Guangxi region.
Cancer investigation - 1 Nov 2006
Gao Feng, Li Chensheng, Li Wei, Chen Lisheng, Tang Zongjiang, Tang Weizhong
Abstract excerpt
To explore the spectrum of p53 gene mutations of sporadic colorectal carcinoma in Guangxi, a Zhuang autonomous region in southern China, we examined exons 2 approximately 11 and exon-intron junctions of p53 gene from 48 patients with sporadic colorectal carcinoma by using single strand conformation polymorphism (SSCP) and DNA direct sequencing. As a result, p53 gene mutations were found in 31.25 percent (15/48)...
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