[A study on the mutation of P53 and K-ras gene in colorectal adenomas and colorectal carcinomas].

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Article

[A study on the mutation of P53 and K-ras gene in colorectal adenomas and colorectal carcinomas].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Nov 2012

Xu Wei, Cheng Yong, Shen Xiong-Fei

Abstract excerpt

OBJECTIVE: To investigate the incidence of P53 and K-ras gene mutation in colorectal adenomas and primary colorectal carcinomas. METHODS: There were 25 normal samples, 38 samples of colorectal adenoma, 78 samples of single primary colorectal cancer and 19 samples of multiple primary colorectal carcinomas (7 synchronous colorectal carcinomas and 12 metachronous colorectal carcinomas) collected in this study. With...

Topics

Adenomatous Polyposis Coli
Aged
Colorectal Neoplasms
Female
Genes, p53
Genes, ras
Humans
Male
Middle Aged
Mutation
Neoplasms, Multiple Primary

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PMID: 23387205

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