Article
Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Jan 2000
Sameer A Syed, ul Rehman Shakeel, Pandith Arshad A, Syeed Nidda, Shah Zaffar A, Chowdhri Nissar A, Wani Khursheed A, Siddiqi Mushtaq A
Abstract excerpt
BACKGROUND/AIM: Colorectal cancer (CRC) is one of the leading malignancies worldwide and has been reported to show geographical variation in its incidence, even within areas of ethnic homogeneity. The aim of this study was to identify p53 and K-ras gene mutations in CRC patients in a Kashmiri population, and to assess whether these mutations are linked with clinicopathological parameters. MATERIALS AND METHODS:...
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