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Article

Implication of K-ras and p53 in colorectal cancer carcinogenesis in Tunisian population cohort.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014

Ines Chaar, Donia Ounissi, Rahma Boughriba, Ben Ammar Azza, Sameh Amara, Khalfallah Taher, Abdelmajid Ben Hmida, Sabeh Mzabi, Saadia Bouraoui

Abstract excerpt

According to the multistep route of genetic alterations in the colorectal adenoma-carcinoma sequence, the complex K-ras/p53 mutation is one of the first alterations to occur and represent an important genetic event in colorectal cancer (CRC). An evaluation of the mutation spectra in K-ras and p53 gene was effected in 167 Tunisian patients with sporadic CRC to determine whether our populations have similar pattern...

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PMID: 24763823
DOI: 10.1007/s13277-014-1874-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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