Article
A Brucella melitensis high-temperature-requirement A (htrA) deletion mutant is attenuated in goats and protects against abortion.
Research in veterinary science - 1 Jan 2000
Phillips R W, Elzer P H, Robertson G T, Hagius S D, Walker J V, Fatemi M B, Enright F M, Roop R M
Abstract excerpt
It has been previously demonstrated that a Brucella melitensis high-temperature-requirement A (htrA) deletion mutant is more susceptible to oxidative killing in vitro than the parental strain and is attenuated in mice. To evaluate the contribution of the B melitensis HtrA protease to virulence in...
Topics
- Abortion, Veterinary
- Animals
- Antibodies, Bacterial
- Bacterial Proteins
- Bacterial Vaccines
- Brucella melitensis
- Brucellosis
- Female
- Fetus
- Gene Deletion
- Goat Diseases
- Goats
- Heat-Shock Proteins
- Mutation
- Periplasmic Proteins