Article
Re-examination of the role of the Brucella melitensis HtrA stress response protease in virulence in pregnant goats.
Veterinary microbiology - 3 Sept 2001
Roop R M, Phillips R W, Hagius S, Walker J V, Booth N J, Fulton W T, Edmonds M D, Elzer P H
Abstract excerpt
Based on previously reported studies describing the experimental infection of pregnant goats with B. melitensis strain RWP5, we proposed that the HtrA protease plays an important role in the virulence of B. melitensis in its natural ruminant host. Subsequent studies, however, have shown that RWP5 is actually an htrA cycL double mutant. In order to definitively evaluate the role of the B. melitensis htrA in...
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