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Article

Evaluating the virulence of a Brucella melitensis hemagglutinin gene in the caprine model.

Vaccine - 1 Oct 2010

Perry Quinesha L, Hagius Sue D, Walker Joel V, Elzer Philip H

Abstract excerpt

With the completion of the genomic sequence of Brucella melitensis 16M, a putative hemagglutinin gene was identified which is present in 16M and absent in Brucella abortus. The possibility of this hemagglutinin being a potential virulence factor was evaluated via gene replacement in B. melitensis yielding 16MΔE and expression in trans in B. abortus 2308-QAE. Utilizing the caprine brucellosis model, colonization...

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Source

Identifiers

PMID: 20362205
DOI: 10.1016/j.vaccine.2010.03.056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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