Article
Further characterization of the TS-4 temperature-sensitive mutant of Toxoplasma gondii in mice.
The Journal of parasitology - 1 Feb 1995
Pinckney R D, Lindsay D S, Blagburn B L
Abstract excerpt
Maternal transmission of Toxoplasma gondii infection to fetuses is important in human and veterinary medicine. Animals, including mice, have been successfully vaccinated with living tachyzoites of the avirulent, nonpersistent, TS-4 temperature-sensitive mutant of T. gondii and have survived challenge infections. We examined in the murine model the persistence of TS-4 infection, transplacental and transmammary...
Topics
- Animals
- Animals, Newborn
- Animals, Suckling
- Antibodies, Protozoan
- Disease Models, Animal
- Female
- Infectious Disease Transmission, Vertical
- Mice
- Mutation
- Pregnancy
- Pregnancy Complications, Parasitic