Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients.

Hepatology (Baltimore, Md.) - 1 Jan 1998

Booth J C, Kumar U, Webster D, Monjardino J, Thomas H C

Abstract excerpt

The hypervariable region (HVR) of the E2/NS1 region of hepatitis C virus (HCV) varies greatly between viral isolates with high rates of genomic change reported during the course of chronic infection. The HVR is thought to encode a structurally unconstrained envelope protein containing several linear B cell epitopes recognized by neutralizing antibody. It has been postulated that amino acid changes in the HVR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Genetic Variation

Share to Hepacivirus

Share to Molecular Sequence Data

Share to Reference Values

Share to Viremia

Source

Identifiers

PMID: 9425941
DOI: 10.1002/hep.510270134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients.PMID 9425941Read ↗

Dynamics of hypervariable region 1 variation in hepatitis C virus infection and correlation with clinical and virological features of liver disease.Semantic proximity Read ↗

Characterization of hypervariable region in hepatitis C virus envelope protein during acute and chronic infection.Semantic proximity Read ↗

Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity.Semantic proximity Read ↗

Acceleration of Hepatitis C Virus Envelope Evolution in Humans Is Consistent with Progressive Humoral Immune Selection during the Transition from Acute to Chronic InfectionSemantic proximity Read ↗

Changes in hypervariable region 1 of the envelope 2 glycoprotein of hepatitis C virus in children and adults with humoral immune defects.Semantic proximity Read ↗

Hypervariable region 1 sequence stability during hepatitis C virus replication in chimpanzees.Semantic proximity Read ↗

Evolution of Hypervariable Region 1 of Hepatitis C Virus in Primary InfectionSemantic proximity Read ↗

Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection.Semantic proximity Read ↗

[Genetic variation characteristics of the envelope region of hepatitis C virus in the patients with chronic hepatitis].Semantic proximity Read ↗

Genetic evolution of structural region of hepatitis C virus in primary infection.Semantic proximity Read ↗

Immunoglobulin mimicry by Hepatitis C Virus envelope protein E2.Semantic proximity Read ↗

Variations in the hypervariable region 1 of the envelope region E2 of hepatitis C virus RNA appear associated with virus persistence independently of liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.