Article
Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients.
Hepatology (Baltimore, Md.) - 1 Jan 1998
Booth J C, Kumar U, Webster D, Monjardino J, Thomas H C
Abstract excerpt
The hypervariable region (HVR) of the E2/NS1 region of hepatitis C virus (HCV) varies greatly between viral isolates with high rates of genomic change reported during the course of chronic infection. The HVR is thought to encode a structurally unconstrained envelope protein containing several lin...
Topics
- Adult
- Agammaglobulinemia
- Amino Acid Sequence
- Base Sequence
- Conserved Sequence
- Female
- Genetic Variation
- Hepacivirus
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Reference Values
- Viremia