Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors.

International journal of cancer - 19 Dec 1997

Breivik J, Lothe R A, Meling G I, Rognum T O, Børresen-Dale A L, Gaudernack G

Abstract excerpt

Mutations in the k-ras and TP53 genes, as well as microsatellite instability (MIN), are frequent genetic alterations in colorectal carcinomas and represent 3 different mechanisms in the carcinogenic process. Both the incidence of colorectal cancer and the frequency of genetic alterations in such tumours have been related to different clinico-pathological variables, including age and gender of the patient and...

Topics

Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
DNA, Neoplasm
Female
Genes, p53
Genes, ras
Humans
Male
Microsatellite Repeats
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Regression Analysis

Sex Factors

Source

Identifiers

PMID: 9421366
DOI: 10.1002/(sici)1097-0215(19971219)74:6<664::aid-ijc18>3.0.co;2-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9421366-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors.PMID 9421366Read ↗

Different mechanisms in the tumorigenesis of proximal and distal colon cancers.Semantic proximity Read ↗

Different genetic features associated with colon and rectal carcinogenesis.Semantic proximity Read ↗

K-ras mutation in colorectal cancer: relations to patient age, sex and tumour locationSemantic proximity Read ↗

Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas.Semantic proximity Read ↗

Are there two sides to colorectal cancer?Semantic proximity Read ↗

Analysis of colorectal cancer morphology in relation to sex, age, location, and family history.Semantic proximity Read ↗

Mutations in the p53 and Ki-ras genes, microsatellite instability and site of tumor origin in colorectal cancer.Semantic proximity Read ↗

Different pathways of colorectal carcinogenesis and their clinical pictures.Semantic proximity Read ↗

p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women.Semantic proximity Read ↗

The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma.Semantic proximity Read ↗

Colorectal cancers choosing sides.Semantic proximity Read ↗

Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.