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Article

Role of gene conversion in generating polymorphisms at major histocompatibility complex loci.

Hereditas - 1 Jan 1997

Ohta T

Abstract excerpt

Multigene families are known to be evolving under continued occurrence of unequal crossing-over and gene conversion, and MHC loci are no exceptions. Population genetic models of diversifying selection, with intra- and inter-locus gene conversion were studied by computer simulations. Weak selection at individual amino acid site is shown to be quite effective in enhancing polymorphisms, if gene conversion occurs....

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Source

Identifiers

PMID: 9420475
DOI: 10.1111/j.1601-5223.1997.00097.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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