Role of gene conversion in generating polymorphisms at major histocompatibility complex loci.

doi:10.1111/j.1601-5223.1997.00097.x

Back to search

Article

Role of gene conversion in generating polymorphisms at major histocompatibility complex loci.

Hereditas - 1 Jan 1997

Ohta T

Abstract excerpt

Multigene families are known to be evolving under continued occurrence of unequal crossing-over and gene conversion, and MHC loci are no exceptions. Population genetic models of diversifying selection, with intra- and inter-locus gene conversion were studied by computer simulations. Weak selectio...

Topics

Alleles
Computer Simulation
Evolution, Molecular
Gene Conversion
Humans
Indians, North American
Indians, South American
Major Histocompatibility Complex
Models, Genetic
Multigene Family
Selection, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.