Generation of MHC class II diversity by intra- and intergenic recombination.

Abstract excerpt

The occurrence and significance of recombination events in the generation of MHC class II diversity were discussed. Evidence that intragenic recombination has contributed to the generation of allelic diversity at a DRB locus in the moose was presented. Intergenic recombination (i.e. exchange of sequence information between nonallelic genes) is expected to be rare and only to play a minor role in the generation of...

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