Gene conversion in the evolution of the human and chimpanzee MHC class I loci.

doi:10.1111/j.1399-0039.1991.tb01889.x

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Article

Gene conversion in the evolution of the human and chimpanzee MHC class I loci.

Tissue antigens - 1 Oct 1991

Kuhner M K, Lawlor D A, Ennis P D, Parham P

Abstract excerpt

Sixty-five DNA sequences from human and chimpanzee major histocompatibility complex class I loci were searched for statistical evidence of past gene conversion. Twenty-four potential conversions were detected; they were distributed across both variable and conserved portions of the gene, and involved both classical and non-classical loci. The majority spanned less than 100 bp, comparable in length to the...

Topics

Alleles
Animals
Base Sequence
Consensus Sequence
Crossing Over, Genetic
DNA
Gene Conversion
Genes, MHC Class I
HLA-A Antigens
HLA-B Antigens
Histocompatibility Antigens
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Major Histocompatibility Complex

Molecular Sequence Data

Multigene Family

Pan troglodytes

Phylogeny

Sequence Alignment

Source

Open in PubMed

Identifiers

PMID: 1801305
DOI: 10.1111/j.1399-0039.1991.tb01889.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1801305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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