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Article

Gene conversion in the evolution of the human and chimpanzee MHC class I loci.

Tissue antigens - 1 Oct 1991

Kuhner M K, Lawlor D A, Ennis P D, Parham P

Abstract excerpt

Sixty-five DNA sequences from human and chimpanzee major histocompatibility complex class I loci were searched for statistical evidence of past gene conversion. Twenty-four potential conversions were detected; they were distributed across both variable and conserved portions of the gene, and involved both classical and non-classical loci. The majority spanned less than 100 bp, comparable in length to the...

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Identifiers

PMID: 1801305
DOI: 10.1111/j.1399-0039.1991.tb01889.x

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