Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection, convergence, and intragenic recombination in HLA diversity.

Genetica - 1 Jan 1998

Takahata N, Satta Y

Abstract excerpt

To account for high degrees of human leukocyte antigen (HLA) diversity, a method is proposed for detecting intragenic recombination or gene conversion separately from parallel substitutions or convergent evolution. An application of the method to HLA protein sequences suggests that intragenic recombination played important roles in HLA-B and DPB1, some in HLA-A and DRB1, and least in HLA-C and DQB1 diversity....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Computer Simulation
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to HLA Antigens

Share to Models, Genetic

Share to Recombination, Genetic

Share to Selection, Genetic

Source

Identifiers

PMID: 9720277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection, convergence, and intragenic recombination in HLA diversity.PMID 9720277Read ↗

Effects of intra-locus recombination of HLA polymorphism.Semantic proximity Read ↗

An apportionment of human HLA diversity.Semantic proximity Read ↗

The noncoding regions of HLA-DRB uncover interlineage recombinations as a mechanism of HLA diversification.Semantic proximity Read ↗

Generation of MHC class II diversity by intra- and intergenic recombination.Semantic proximity Read ↗

Allelic diversity is generated by intraexon sequence exchange at the DRB1 locus of primates.Semantic proximity Read ↗

The neutral theory and natural selection in the HLA region.Semantic proximity Read ↗

How HLA diversity is apportioned: influence of selection and relevance to transplantation.Semantic proximity Read ↗

Footprints of intragenic recombination at HLA lociSemantic proximity Read ↗

Role of gene conversion in generating polymorphisms at major histocompatibility complex loci.Semantic proximity Read ↗

Contrasting roles of interallelic recombination at the HLA-A and HLA-B loci.Semantic proximity Read ↗

Population Differentiation at the <i>HLA</i> GenesSemantic proximity Read ↗

Patterns of reticulate evolution for the classical class I and II HLA loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.