Article
Molecular evolution in a multisite nearly neutral mutation model.
Journal of molecular evolution - 1 Jan 2000
Tachida H
Abstract excerpt
A simple nearly neutral mutation model of protein evolution was studied using computer simulation assuming a constant population size. In this model, a gene consists of a finite number of codons and there is no recombination within a gene. Each codon has two replacement and one silent sites. The fitness of a gene was determined multiplicatively by amino acids specified by codons (the independent multicodon...
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