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Article

Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy.

Journal of virology - 1 Jan 1998

van't Wout A B, Ran L J, Kuiken C L, Kootstra N A, Pals S T, Schuitemaker H

Abstract excerpt

We studied the temporal relationship between human immunodeficiency type 1 (HIV-1) quasispecies in tissues and in peripheral blood mononuclear cells (PBMC) of infected individuals. Sequential PBMC and tissue samples from various organs obtained at autopsy from three patients who died of AIDS-related complications were available for analysis. Biological HIV-1 clones were isolated from PBMC samples, and cellular...

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Identifiers

PMID: 9420250
DOI: 10.1128/JVI.72.1.488-496.1998
PMCID: PMC109399

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