Article
HIV type 1 envelope quasispecies in the thymus and lymph Nodes of AIDS patients.
AIDS research and human retroviruses - 20 Jan 2002
Alves Katia, Canzian Mauro, Delwart E L
Abstract excerpt
To test for the presence of HIV syncytium-inducing (SI) strains in the thymus in vivo we sequenced HIV envelope V3 variants from thymic and peripheral lymph node tissues of three subjects who died of AIDS. Phylogenetic analysis of proviral sequences derived by direct sequencing of multiple independent PCRs showed that the HIV-1 quasispecies did not segregate into distinct clusters in the thymus versus lymph...
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