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Article

Subtype C HIV-1 reservoirs throughout the body in ART-suppressed individuals

23 Oct 2022

Abstract excerpt

Subtype B HIV-1 reservoirs have been intensively investigated, but reservoirs in other subtypes and how they respond to antiretroviral therapy (ART) is substantially less established. To characterize subtype C HIV-1 reservoirs, we implemented postmortem frozen, as well as formalin fixed paraffin embedded (FFPE) tissue sampling of central nervous system (CNS) and peripheral tissues. HIV-1 LTR, gag, envelope (env)...

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PMID: 36278485
DOI: 10.1172/jci.insight.162604

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