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Article

HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer.

Journal of virology - 15 Oct 2016

Rose Rebecca, Lamers Susanna L, Nolan David J, Maidji Ekaterina, Faria N R, Pybus Oliver G, Dollar James J, Maruniak Samuel A, McAvoy Andrew C, Salemi Marco, Stoddart Cheryl A, Singer Elyse J, McGrath Michael S

Abstract excerpt

UNLABELLED: While combined antiretroviral therapy (cART) can result in undetectable plasma viral loads, it does not eradicate HIV infection. Furthermore, HIV-infected individuals while on cART remain at an increased risk of developing serious comorbidities, such as cancer, neurological disease, and atherosclerosis, suggesting that during cART, tissue-based HIV may contribute to such pathologies. We obtained DNA...

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PMID: 27466425
DOI: 10.1128/JVI.00684-16
PMCID: PMC5044847

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