Article
Infectious cellular load in human immunodeficiency virus type 1 (HIV-1)-infected individuals and susceptibility of peripheral blood mononuclear cells from their exposed partners to non-syncytium-inducing HIV-1 as major determinants for HIV-1 transmission in homosexual couples.
Journal of virology - 1 Jan 1998
Blaak H, van't Wout A B, Brouwer M, Cornelissen M, Kootstra N A, Albrecht-van Lent N, Keet R P, Goudsmit J, Coutinho R A, Schuitemaker H
Abstract excerpt
To study risk factors for homosexual transmission of human immunodeficiency virus type 1 (HIV-1), we compared 10 monogamous homosexual couples between whom transmission of HIV-1 had occurred with 10 monogamous homosexual couples between whom HIV-1 transmission had not occurred despite high-risk sexual behavior. In the group of individuals who did not transmit virus, peripheral cellular infectious load was lower...
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