Article
Lack of infection in HIV-exposed individuals is associated with a strong CD8(+) cell noncytotoxic anti-HIV response.
Proceedings of the National Academy of Sciences of the United States of America - 2 Feb 1999
Stranford S A, Skurnick J, Louria D, Osmond D, Chang S Y, Sninsky J, Ferrari G, Weinhold K, Lindquist C, Levy J A
Abstract excerpt
Individuals repeatedly exposed to HIV, but who remain uninfected, form a population enriched for persons likely to have either natural or acquired resistance to the virus. We have studied four such exposed uninfected cohorts, representing 60 individuals, for evidence of protective immunity. This...
Topics
- Adult
- CD8-Positive T-Lymphocytes
- Cells, Cultured
- Female
- Genotype
- HIV Infections
- HIV-1
- Humans
- Immunity, Innate
- Male
- Middle Aged
- Receptors, CCR5
- Risk Factors
- Sexual Behavior
- T-Lymphocyte Subsets