Article
Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.
Annals of internal medicine - 1 May 1993
Koot M, Keet I P, Vos A H, de Goede R E, Roos M T, Coutinho R A, Miedema F, Schellekens P T, Tersmette M
Abstract excerpt
OBJECTIVE: To investigate the relation between detection of syncytium-inducing (SI), human immunodeficiency virus type 1 (HIV-1) variants, rate of CD4+ cell decline, and clinical progression. DESIGN: Prospective study during a 2.5-year follow-up period; cohort study with pairwise matched controls...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- CD4-Positive T-Lymphocytes
- Cell Line
- Cohort Studies
- Giant Cells
- HIV Infections
- HIV-1
- Humans
- Incidence
- Leukocyte Count
- Male
- Middle Aged
- Phenotype
- Prevalence
- Prognosis
- Proportional Hazards Models
- Prospective Studies