Article
Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization.
The Journal of biological chemistry - 26 Dec 1997
Vassilatis D K, Arena J P, Plasterk R H, Wilkinson H A, Schaeffer J M, Cully D F, Van der Ploeg L H
Abstract excerpt
Avermectins are a class of macrocyclic lactones that is widely used in crop protection and to treat helminth infections in man and animals. Two complementary DNAs (GluClalpha and GluClbeta) encoding chloride channels that are gated by avermectin and glutamate, respectively, were isolated from Cae...
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