Article
Decreased emodepside sensitivity in unc-49 γ-aminobutyric acid (GABA)-receptor-deficient Caenorhabditis elegans.
International journal for parasitology - 1 Jul 2012
Miltsch Sandra M, Krücken Jürgen, Demeler Janina, Janssen I Jana I, Krüger Nina, Harder Achim, von Samson-Himmelstjerna Georg
Abstract excerpt
Emodepside, a semi-synthetic derivative of PF1022A, belongs to a new class of anthelmintic drugs, the cyclooctadepsipeptides, and shows good efficacy against macrocyclic lactone-, levamisole- or benzimidazole-resistant nematode populations. Although putative receptors for emodepside have already...
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